• Pharmacological management of modifiable cardiovascular risk factors (blood pressure and lipids) following diagnosis of myocardial infarction, stroke and diabetes: Comparison between population-based studies in Russia and Norway 

      Cook, Sarah Anne; Hopstock, Laila Arnesdatter; Eggen, Anne Elise; Bates, Katie; Iakunchykova, Olena; Kontsevaya, Anna; McKee, Martin; Schirmer, Henrik; Voevoda, Michael; Kudryavtsev, Alexander V; Malyutina, Sofia; Leon, David A. (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-05-19)
      <i>Background</i> - Cardiovascular disease (CVD) mortality is substantially higher in Russia than in neighbouring Norway. We aimed to compare blood pressure- and lipid-lowering medication use and proportion meeting treatment targets between general population samples in the two countries in those with CVD and diabetes.<p><p> <i>Methods</i> - The study population was adults aged 40–69 years reporting ...
    • Studying accelerated cardiovascular ageing in Russian adults through a novel deep-learning ECG biomarker 

      Benavente, Ernest Diez; Jimenez-Lopez, Francisco; Attia, Zachi I.; Malyutina, Sofia; Kudryavtsev, Alexander; Ryabikov, Andrey; Friedman, Paul A.; Kapa, Suraj; Voevoda, Michael; Perel, Pablo; Schirmer, Henrik; Hughes, Alun D.; Clark, Taane; Leon, David A. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-01-25)
      Background: A non-invasive, easy-to-access marker of accelerated cardiac ageing would provide novel insights into the mechanisms and aetiology of cardiovascular disease (CVD) as well as contribute to risk stratification of those who have not had a heart or circulatory event. Our hypothesis is that differences between an ECG-predicted and chronologic age of participants (δage) would reflect accelerated ...